pad4 rabbit anti mouse primary antibody (Proteintech)
Structured Review

Pad4 Rabbit Anti Mouse Primary Antibody, supplied by Proteintech, used in various techniques. Bioz Stars score: 95/100, based on 87 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pad4+rabbit+anti+mouse+primary+antibody/pm38396985-354-0-5?v=Proteintech
Average 95 stars, based on 87 article reviews
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1) Product Images from "Loss of 15-Lipoxygenase in Retinodegenerative RCS Rats."
Article Title: Loss of 15-Lipoxygenase in Retinodegenerative RCS Rats.
Journal: International journal of molecular sciences
doi: 10.3390/ijms25042309
Figure Legend Snippet: Figure 5. ONL PR counts and retinal PAD4 immunofluorescence staining. IVT NAP1051 adminis- tration promotes PR preservation in a dosage-dependent manner (A), which was correlated with PR counts (B). Adjacent histological sections were stained with anti-PAD4 (red) antibodies and DAPI (blue) (C), which showed reduced retinal PAD4 fluorescence intensity (D). Data represented as median ± 95% CI, * p < 0.05, Kruskal–Wallis with Dunn’s correction.
Techniques Used: Immunofluorescence, Staining, Preserving, Fluorescence
Figure Legend Snippet: Figure 9. Effects on rd10 mice treated with NAP1051. rd10 mice treated with NAP1051 from p15 to p26 showed ONL preservation on OCT (arrows) and H&E on p26 (A). NAP1051 was able to preserve ONL thickness (B) and PR counts (C). OCT-FAF showed NAP1051 reduced hyperpigmentation on p26 (D,E). Correlations between the ONL PR counts and FAF hyperpigmentation were evaluated and demonstrated a negative linear correlation (R2 = 0.9) where fewer hyperpigmentation spots were correlated to increased ONL PR nuclei (F). Retinal PAD4 immunofluorescence staining was reduced for animals treated with 37.5 mg/kg/BID (G) corresponding with reduced retinal H3Cit, but not to a statistically significant level (H). The oxidative stress marker malondialdehyde (MDA) was statisti- cally significantly reduced at the 37.5 mg/kg/BID dosage (I). Data represented as median ± 95% CI, * p < 0.05, ** p < 0.01, Kruskal–Wallis test with Dunn’s correction. The number of PRs in the ONL and hyperpigmentation spots seen in FAF were enumerated using ImageJ/FIJI (ver 2.3.0).
Techniques Used: Preserving, Immunofluorescence, Staining, Marker